elsevier induced pluripotent stem cells yamanaka

Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology. He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA), and in 2021, he was elected affiliate member of The World Academy of Sciences (TWAS). His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. Here, we demonstrate the generation of iPS cells from adult human dermal fibroblasts with the same four factors: Oct3/4, Sox2, Klf4, and c-Myc. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. We previously reported generation of induced pluripotent stem (iPS) cells, capable of germline transmission, from mouse somatic cells by transduction of four defined transcription factors. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. Then, he joined as a postdoc in stem cell biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine in New York. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Alexander Birbrair received his bachelor’s biomedical degree from Santa Cruz State University in Brazil. Xeno-Free Cultivation of Human Induced Pluripotent Stem Cells for Clinical Applicationsĭr. Scalable Expansion of Human Pluripotent Stem Cells for Biomanufacturing Cellular Therapeuticsġ2. CRISPR/Cas9 Technologies to Manipulate Human Induced Pluripotent Stem Cellsġ1. Bacteria to Form Induced Pluripotent Stem Cellsġ0. Realization of the full potential of human induced pluripotent stem cells (hiPSC) in clinical applications requires the development of well-defined culture. One Plus One Could be Greater than Two: Combining the Powers of Somatic Cell Nuclear Transfer with Yamanaka’s Factors in Generating Clinical Grade Human Pluripotent Stem Cellsĩ. Emerging Strategies for Scalable Human Induced Pluripotent Stem Cell and Expansion and DifferentiationĨ. Combining Bioscaffolds and iPCSs in the Treatment of Neural Trauma and Alzheimer’s diseaseħ. Decellularized Liver Extracellular Matrix for iPSC-based Liver EngineeringĦ. Lentiviral Vectors as The Delivery Vehicles for Transduction into iPSCs: Shortcomings and Benefitsĥ. PiggyBac Vectors in Pluripotent Stem Cell Research and ApplicationsĤ. Current Reprogramming Methods to Generate High Quality iPSCsģ.

Elsevier induced pluripotent stem cells yamanaka